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Loganin Exerts Sedative and Hypnotic Effects via Modulation of the Serotonergic System and GABAergic Neurons
Corni fructus, the fruit of Cornus officinalis Sieb. et Zucc., has been used as a tonic for the kidney in China for thousands of years. Loganin is one of the major constituents derived from Corni fructus. In this study, we revealed the sedative and hypnotic activity of loganin and investigated its m...
Autores principales: | Shi, Rui, Han, Yan, Yan, Yu, Qiao, Hao-Yi, He, Jun, Lian, Wen-Wen, Xia, Cong-Yuan, Li, Ting-Li, Zhang, Wei-Ku, Xu, Jie-Kun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491506/ https://www.ncbi.nlm.nih.gov/pubmed/31068813 http://dx.doi.org/10.3389/fphar.2019.00409 |
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