Antimicrobial Peptide LL-37 Facilitates Intracellular Uptake of RNA Aptamer Apt 21-2 Without Inducing an Inflammatory or Interferon Response

RNA aptamers are synthetic single stranded RNA oligonucleotides that function analogously to antibodies. Recently, they have shown promise for use in treating inflammatory skin disease as, unlike antibody-based biologics, they are able to enter the skin following topical administration. However, it...

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Detalles Bibliográficos
Autores principales: Macleod, Tom, Ward, Joseph, Alase, Adewonuola A., Bridgewood, Charlie, Wittmann, Miriam, Stonehouse, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491520/
https://www.ncbi.nlm.nih.gov/pubmed/31068939
http://dx.doi.org/10.3389/fimmu.2019.00857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491520/
https://www.ncbi.nlm.nih.gov/pubmed/31068939
http://dx.doi.org/10.3389/fimmu.2019.00857

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