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A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction
Chronic diseases are one of the biggest threats to human life. It is clinically significant to predict the chronic disease prior to diagnosis time and take effective therapy as early as possible. In this work, we use problem transform methods to convert the chronic diseases prediction into a multi-l...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491565/ https://www.ncbi.nlm.nih.gov/pubmed/31068968 http://dx.doi.org/10.3389/fgene.2019.00351 |
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author | Zhang, Xiaoqing Zhao, Hongling Zhang, Shuo Li, Runzhi |
author_facet | Zhang, Xiaoqing Zhao, Hongling Zhang, Shuo Li, Runzhi |
author_sort | Zhang, Xiaoqing |
collection | PubMed |
description | Chronic diseases are one of the biggest threats to human life. It is clinically significant to predict the chronic disease prior to diagnosis time and take effective therapy as early as possible. In this work, we use problem transform methods to convert the chronic diseases prediction into a multi-label classification problem and propose a novel convolutional neural network (CNN) architecture named GroupNet to solve the multi-label chronic disease classification problem. Binary Relevance (BR) and Label Powerset (LP) methods are adopted to transform multiple chronic disease labels. We present the correlated loss as the loss function used in the GroupNet, which integrates the correlation coefficient between different diseases. The experiments are conducted on the physical examination datasets collected from a local medical center. In the experiments, we compare GroupNet with other methods and models. GroupNet outperforms others and achieves the best accuracy of 81.13%. |
format | Online Article Text |
id | pubmed-6491565 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-64915652019-05-08 A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction Zhang, Xiaoqing Zhao, Hongling Zhang, Shuo Li, Runzhi Front Genet Genetics Chronic diseases are one of the biggest threats to human life. It is clinically significant to predict the chronic disease prior to diagnosis time and take effective therapy as early as possible. In this work, we use problem transform methods to convert the chronic diseases prediction into a multi-label classification problem and propose a novel convolutional neural network (CNN) architecture named GroupNet to solve the multi-label chronic disease classification problem. Binary Relevance (BR) and Label Powerset (LP) methods are adopted to transform multiple chronic disease labels. We present the correlated loss as the loss function used in the GroupNet, which integrates the correlation coefficient between different diseases. The experiments are conducted on the physical examination datasets collected from a local medical center. In the experiments, we compare GroupNet with other methods and models. GroupNet outperforms others and achieves the best accuracy of 81.13%. Frontiers Media S.A. 2019-04-24 /pmc/articles/PMC6491565/ /pubmed/31068968 http://dx.doi.org/10.3389/fgene.2019.00351 Text en Copyright © 2019 Zhang, Zhao, Zhang and Li. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Genetics Zhang, Xiaoqing Zhao, Hongling Zhang, Shuo Li, Runzhi A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction |
title | A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction |
title_full | A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction |
title_fullStr | A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction |
title_full_unstemmed | A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction |
title_short | A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction |
title_sort | novel deep neural network model for multi-label chronic disease prediction |
topic | Genetics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491565/ https://www.ncbi.nlm.nih.gov/pubmed/31068968 http://dx.doi.org/10.3389/fgene.2019.00351 |
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