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A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction

Chronic diseases are one of the biggest threats to human life. It is clinically significant to predict the chronic disease prior to diagnosis time and take effective therapy as early as possible. In this work, we use problem transform methods to convert the chronic diseases prediction into a multi-l...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoqing, Zhao, Hongling, Zhang, Shuo, Li, Runzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491565/
https://www.ncbi.nlm.nih.gov/pubmed/31068968
http://dx.doi.org/10.3389/fgene.2019.00351
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author Zhang, Xiaoqing
Zhao, Hongling
Zhang, Shuo
Li, Runzhi
author_facet Zhang, Xiaoqing
Zhao, Hongling
Zhang, Shuo
Li, Runzhi
author_sort Zhang, Xiaoqing
collection PubMed
description Chronic diseases are one of the biggest threats to human life. It is clinically significant to predict the chronic disease prior to diagnosis time and take effective therapy as early as possible. In this work, we use problem transform methods to convert the chronic diseases prediction into a multi-label classification problem and propose a novel convolutional neural network (CNN) architecture named GroupNet to solve the multi-label chronic disease classification problem. Binary Relevance (BR) and Label Powerset (LP) methods are adopted to transform multiple chronic disease labels. We present the correlated loss as the loss function used in the GroupNet, which integrates the correlation coefficient between different diseases. The experiments are conducted on the physical examination datasets collected from a local medical center. In the experiments, we compare GroupNet with other methods and models. GroupNet outperforms others and achieves the best accuracy of 81.13%.
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spelling pubmed-64915652019-05-08 A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction Zhang, Xiaoqing Zhao, Hongling Zhang, Shuo Li, Runzhi Front Genet Genetics Chronic diseases are one of the biggest threats to human life. It is clinically significant to predict the chronic disease prior to diagnosis time and take effective therapy as early as possible. In this work, we use problem transform methods to convert the chronic diseases prediction into a multi-label classification problem and propose a novel convolutional neural network (CNN) architecture named GroupNet to solve the multi-label chronic disease classification problem. Binary Relevance (BR) and Label Powerset (LP) methods are adopted to transform multiple chronic disease labels. We present the correlated loss as the loss function used in the GroupNet, which integrates the correlation coefficient between different diseases. The experiments are conducted on the physical examination datasets collected from a local medical center. In the experiments, we compare GroupNet with other methods and models. GroupNet outperforms others and achieves the best accuracy of 81.13%. Frontiers Media S.A. 2019-04-24 /pmc/articles/PMC6491565/ /pubmed/31068968 http://dx.doi.org/10.3389/fgene.2019.00351 Text en Copyright © 2019 Zhang, Zhao, Zhang and Li. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Zhang, Xiaoqing
Zhao, Hongling
Zhang, Shuo
Li, Runzhi
A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction
title A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction
title_full A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction
title_fullStr A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction
title_full_unstemmed A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction
title_short A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction
title_sort novel deep neural network model for multi-label chronic disease prediction
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491565/
https://www.ncbi.nlm.nih.gov/pubmed/31068968
http://dx.doi.org/10.3389/fgene.2019.00351
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