Development and application of a high-content virion display human GPCR array

Human G protein-coupled receptors (GPCRs) respond to various ligands and stimuli. However, GPCRs rely on membrane for proper folding, making their biochemical properties difficult to study. By displaying GPCRs in viral envelopes, we fabricated a Virion Display (VirD) array containing 315 non-olfacto...

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Detalles Bibliográficos
Autores principales: Syu, Guan-Da, Wang, Shih-Chin, Ma, Guangzhong, Liu, Shuang, Pearce, Donna, Prakash, Atish, Henson, Brandon, Weng, Lien-Chun, Ghosh, Devlina, Ramos, Pedro, Eichinger, Daniel, Pino, Ignacio, Dong, Xinzhong, Xiao, Jie, Wang, Shaopeng, Tao, Nongjian, Kim, Kwang Sik, Desai, Prashant J., Zhu, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491619/
https://www.ncbi.nlm.nih.gov/pubmed/31040288
http://dx.doi.org/10.1038/s41467-019-09938-9

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