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TGF-β1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM
BACKGROUND: Hepatic stellate cell (HSC) activation induced by transforming growth factor β1 (TGF-β1) plays a pivotal role in fibrogenesis, while the complex downstream mediators of TGF-β1 in such process are largely unknown. METHODS: We performed pharmacoproteomic profiling of the mice liver tissues...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491716/ https://www.ncbi.nlm.nih.gov/pubmed/30926424 http://dx.doi.org/10.1016/j.ebiom.2019.03.058 |