TGF-β1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM

BACKGROUND: Hepatic stellate cell (HSC) activation induced by transforming growth factor β1 (TGF-β1) plays a pivotal role in fibrogenesis, while the complex downstream mediators of TGF-β1 in such process are largely unknown. METHODS: We performed pharmacoproteomic profiling of the mice liver tissues...

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Detalles Bibliográficos
Autores principales: Wang, Kuifeng, Fang, Shanhua, Liu, Qian, Gao, Jing, Wang, Xiaoning, Zhu, Hongwen, Zhu, Zhenyun, Ji, Feihong, Wu, Jiasheng, Ma, Yueming, Hu, Lihong, Shen, Xu, Gao, Daming, Zhu, Jiansheng, Liu, Ping, Zhou, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491716/
https://www.ncbi.nlm.nih.gov/pubmed/30926424
http://dx.doi.org/10.1016/j.ebiom.2019.03.058

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