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The Fungal CYP51s: Their Functions, Structures, Related Drug Resistance, and Inhibitors

CYP51 (Erg11) belongs to the cytochrome P450 monooxygenase (CYP) superfamily and mediates a crucial step of the synthesis of ergosterol, which is a fungal-specific sterol. It is also the target of azole drugs in clinical practice. In recent years, researches on fungal CYP51 have stepped into a new s...

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Detalles Bibliográficos
Autores principales:	Zhang, Jingxiang, Li, Liping, Lv, Quanzhen, Yan, Lan, Wang, Yan, Jiang, Yuanying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491756/ https://www.ncbi.nlm.nih.gov/pubmed/31068906 http://dx.doi.org/10.3389/fmicb.2019.00691

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