Whole Exome Sequencing of Cell-Free DNA for Early Lung Cancer: A Pilot Study to Differentiate Benign From Malignant CT-Detected Pulmonary Lesions

Introduction: Indeterminate pulmonary lesions (IPL) detected by CT pose a significant clinical challenge, frequently necessitating long-term surveillance or biopsy for diagnosis. In this pilot investigation, we performed whole exome sequencing (WES) of plasma cell free (cfDNA) and matched germline D...

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Detalles Bibliográficos
Autores principales: Tailor, Tina D., Rao, Xiayu, Campa, Michael J., Wang, Jing, Gregory, Simon G., Patz Jr., Edward F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491780/
https://www.ncbi.nlm.nih.gov/pubmed/31069172
http://dx.doi.org/10.3389/fonc.2019.00317

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