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In silico ADME and Toxicity Prediction of Ceftazidime and Its Impurities
To improve the quality control of drugs, we predicted the absorption, distribution, metabolism, excretion, and toxicity (ADMET) of ceftazidime (CAZ) and its impurities via in silico methods. We used three types of quantitative structure-activity relationship and docking software for precise predicti...
Autores principales: | Han, Ying, Zhang, Jingpu, Hu, Chang Qin, Zhang, Xia, Ma, Bufang, Zhang, Peipei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491819/ https://www.ncbi.nlm.nih.gov/pubmed/31068821 http://dx.doi.org/10.3389/fphar.2019.00434 |
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