Differential Aggregation and Phosphorylation of Alpha Synuclein in Membrane Compartments Associated With Parkinson Disease

The aggregation of α-synuclein (α-syn) is a major factor behind the onset of Parkinson’s disease (PD). Sublocalization of this protein may be relevant for the formation of multimeric α-syn oligomeric configurations, insoluble aggregates that form Lewy bodies in PD brains. Processing of this protein...

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Detalles Bibliográficos
Autores principales: Canerina-Amaro, Ana, Pereda, Daniel, Diaz, Mario, Rodriguez-Barreto, Deiene, Casañas-Sánchez, Verónica, Heffer, Marija, Garcia-Esparcia, Paula, Ferrer, Isidro, Puertas-Avendaño, Ricardo, Marin, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491821/
https://www.ncbi.nlm.nih.gov/pubmed/31068782
http://dx.doi.org/10.3389/fnins.2019.00382

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