Cargando…
Atrial Transcriptional Profiles of Molecular Targets Mediating Electrophysiological Function in Aging and Pgc-1β Deficient Murine Hearts
BACKGROUND: Deficiencies in the transcriptional co-activator, peroxisome proliferative activated receptor, gamma, coactivator-1β are implicated in deficient mitochondrial function. The latter accompanies clinical conditions including aging, physical inactivity, obesity, and diabetes. Recent electrop...
Autores principales: | Edling, Charlotte E., Fazmin, Ibrahim T., Chadda, Karan R., Ahmad, Shiraz, Valli, Haseeb, Huang, Christopher L.-H., Jeevaratnam, Kamalan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491872/ https://www.ncbi.nlm.nih.gov/pubmed/31068841 http://dx.doi.org/10.3389/fphys.2019.00497 |
Ejemplares similares
-
Gene and Protein Expression Profile of Selected Molecular Targets Mediating Electrophysiological Function in Pgc-1α Deficient Murine Atria
por: Chadda, Karan R., et al.
Publicado: (2018) -
Molecular basis of ventricular arrhythmogenicity in a Pgc-1α deficient murine model
por: Saadeh, Khalil, et al.
Publicado: (2021) -
Ageing in Pgc-1β(−/−) mice modelling mitochondrial dysfunction induces differential expression of a range of genes regulating ventricular electrophysiology
por: Edling, Charlotte E., et al.
Publicado: (2019) -
Molecular basis of arrhythmic substrate in ageing murine peroxisome proliferator-activated receptor γ co-activator deficient hearts modelling mitochondrial dysfunction
por: Edling, Charlotte E., et al.
Publicado: (2019) -
Age-dependent atrial arrhythmic phenotype secondary to mitochondrial dysfunction in Pgc-1β deficient murine hearts
por: Valli, Haseeb, et al.
Publicado: (2017)