Genomic landscape of allelic imbalance in premalignant atypical adenomatous hyperplasias of the lung

BACKGROUND: Genomic investigation of atypical adenomatous hyperplasia (AAH), the only known precursor lesion to lung adenocarcinomas (LUAD), presents challenges due to the low mutant cell fractions. This necessitates sensitive methods for detection of chromosomal aberrations to better study the role...

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Detalles Bibliográficos
Autores principales: Sivakumar, Smruthy, San Lucas, F. Anthony, Jakubek, Yasminka A., McDowell, Tina L., Lang, Wenhua, Kallsen, Noah, Peyton, Shanna, Davies, Gareth E., Fukuoka, Junya, Yatabe, Yasushi, Zhang, Jianjun, Futreal, P. Andrew, Fowler, Jerry, Fujimoto, Junya, Ehli, Erik A., Hawk, Ernest T., Wistuba, Ignacio I., Kadara, Humam, Scheet, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491940/
https://www.ncbi.nlm.nih.gov/pubmed/30905849
http://dx.doi.org/10.1016/j.ebiom.2019.03.020

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