Molecular understanding of pharmacological treatment of osteoporosis

Osteoporosis is a serious health concern, particularly in aged societies. The burden of osteoporosis with its associated morbidity and mortality due to fracture has become a critical socioeconomic problem. Skeletal integrity is maintained through a balance of bone resorption and bone formation. The...

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Detalles Bibliográficos
Autor principal: Tanaka, Sakae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: British Editorial Society of Bone and Joint Surgery 2019
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491949/
https://www.ncbi.nlm.nih.gov/pubmed/31057953
http://dx.doi.org/10.1302/2058-5241.4.180018
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author Tanaka, Sakae
author_facet Tanaka, Sakae
author_sort Tanaka, Sakae
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description Osteoporosis is a serious health concern, particularly in aged societies. The burden of osteoporosis with its associated morbidity and mortality due to fracture has become a critical socioeconomic problem. Skeletal integrity is maintained through a balance of bone resorption and bone formation. The bone turnover process, called bone remodelling. Recently, a number of anti-osteoporosis drugs with excellent anti-osteoporosis and fracture effects have been developed. They are mainly classified into two groups according to their effects on bone remodelling: anti-resorptive agents and anabolic agents. Cite this article: EFORT Open Rev 2019;4:158-164. DOI: 10.1302/2058-5241.4.180018
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spelling pubmed-64919492019-05-03 Molecular understanding of pharmacological treatment of osteoporosis Tanaka, Sakae EFORT Open Rev Basic Science Osteoporosis is a serious health concern, particularly in aged societies. The burden of osteoporosis with its associated morbidity and mortality due to fracture has become a critical socioeconomic problem. Skeletal integrity is maintained through a balance of bone resorption and bone formation. The bone turnover process, called bone remodelling. Recently, a number of anti-osteoporosis drugs with excellent anti-osteoporosis and fracture effects have been developed. They are mainly classified into two groups according to their effects on bone remodelling: anti-resorptive agents and anabolic agents. Cite this article: EFORT Open Rev 2019;4:158-164. DOI: 10.1302/2058-5241.4.180018 British Editorial Society of Bone and Joint Surgery 2019-04-29 /pmc/articles/PMC6491949/ /pubmed/31057953 http://dx.doi.org/10.1302/2058-5241.4.180018 Text en © 2019 The author(s) https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-Non Commercial 4.0 International (CC BY-NC 4.0) licence (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed.
spellingShingle Basic Science
Tanaka, Sakae
Molecular understanding of pharmacological treatment of osteoporosis
title Molecular understanding of pharmacological treatment of osteoporosis
title_full Molecular understanding of pharmacological treatment of osteoporosis
title_fullStr Molecular understanding of pharmacological treatment of osteoporosis
title_full_unstemmed Molecular understanding of pharmacological treatment of osteoporosis
title_short Molecular understanding of pharmacological treatment of osteoporosis
title_sort molecular understanding of pharmacological treatment of osteoporosis
topic Basic Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491949/
https://www.ncbi.nlm.nih.gov/pubmed/31057953
http://dx.doi.org/10.1302/2058-5241.4.180018
work_keys_str_mv AT tanakasakae molecularunderstandingofpharmacologicaltreatmentofosteoporosis

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