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Rapamycin administration is not a valid therapeutic strategy for every case of mitochondrial disease
BACKGROUND: The vast majority of mitochondrial disorders have limited the clinical management to palliative care. Rapamycin has emerged as a potential therapeutic drug for mitochondrial diseases since it has shown therapeutic benefits in a few mouse models of mitochondrial disorders. However, the un...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492073/ https://www.ncbi.nlm.nih.gov/pubmed/30898651 http://dx.doi.org/10.1016/j.ebiom.2019.03.025 |