Fine‐Tuning of Sirtuin 1 Expression Is Essential to Protect the Liver From Cholestatic Liver Disease

Cholestasis comprises aetiologically heterogeneous conditions characterized by accumulation of bile acids in the liver that actively contribute to liver damage. Sirtuin 1 (SIRT1) regulates liver regeneration and bile acid metabolism by modulating farnesoid X receptor (FXR); we here investigate its r...

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Detalles Bibliográficos
Autores principales: Blokker, Britt A., Maijo, Monica, Echeandia, Marta, Galduroz, Mikel, Patterson, Angela M., Ten, Anna, Philo, Mark, Schungel, Rebecca, Gutierrez‐de Juan, Virginia, Halilbasic, Emina, Fuchs, Claudia, Le Gall, Gwenaelle, Milkiewicz, Malgorzata, Milkiewicz, Piotr, Banales, Jesus M., Rushbrook, Simon M., Mato, José M., Trauner, Michael, Müller, Michael, Martínez‐Chantar, María Luz, Varela‐Rey, Marta, Beraza, Naiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492079/
https://www.ncbi.nlm.nih.gov/pubmed/30229970
http://dx.doi.org/10.1002/hep.30275

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