Proteomic Evidence of Biological Aging in a Child with a Compound Heterozygous ZMPSTE24 Mutation

BACKGROUND: Progeria‐like syndromes offer a unique insight into aging. Here the case of a boy affected with mandibuloacral dysplasia and compound heterozygous mutations in ZMPSTE24 is presented. METHODS: Capillary electrophoresis‐mass spectroscopy is used for proteome analysis to analyze peptides pr...

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Detalles Bibliográficos
Autores principales: Lucas‐Herald, Angela K, Zürbig, Petra, Mason, Avril, Kinning, Esther, Brown, Catriona E, Mansoorian, Bahareh, Mullen, William, Ahmed, Syed Faisal, Delles, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Dataset Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492098/
https://www.ncbi.nlm.nih.gov/pubmed/30548811
http://dx.doi.org/10.1002/prca.201800135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492098/
https://www.ncbi.nlm.nih.gov/pubmed/30548811
http://dx.doi.org/10.1002/prca.201800135

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