Cytome micronucleus assays with a metabolically competent human derived liver cell line (Huh6): A promising approach for routine testing of chemicals?

One of the main problems of in vitro genotoxicity tests is the inadequate representation of drug metabolizing enzymes in most indicator cell lines which are currently used. We identified recently a human derived liver cell line (Huh6) which detected induction of DNA damage by representatives of diff...

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Detalles Bibliográficos
Autores principales: Mišík, Miroslav, Nersesyan, Armen, Bolognesi, Claudia, Kundi, Michael, Ferk, Franziska, Knasmueller, Siegfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492180/
https://www.ncbi.nlm.nih.gov/pubmed/30408237
http://dx.doi.org/10.1002/em.22254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492180/
https://www.ncbi.nlm.nih.gov/pubmed/30408237
http://dx.doi.org/10.1002/em.22254

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