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Cytome micronucleus assays with a metabolically competent human derived liver cell line (Huh6): A promising approach for routine testing of chemicals?
One of the main problems of in vitro genotoxicity tests is the inadequate representation of drug metabolizing enzymes in most indicator cell lines which are currently used. We identified recently a human derived liver cell line (Huh6) which detected induction of DNA damage by representatives of diff...
Autores principales: | Mišík, Miroslav, Nersesyan, Armen, Bolognesi, Claudia, Kundi, Michael, Ferk, Franziska, Knasmueller, Siegfried |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492180/ https://www.ncbi.nlm.nih.gov/pubmed/30408237 http://dx.doi.org/10.1002/em.22254 |
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