Cargando…
Reliable heritability estimation using sparse regularization in ultrahigh dimensional genome-wide association studies
BACKGROUND: Data from genome-wide association studies (GWASs) have been used to estimate the heritability of human complex traits in recent years. Existing methods are based on the linear mixed model, with the assumption that the genetic effects are random variables, which is opposite to the fixed e...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492418/ https://www.ncbi.nlm.nih.gov/pubmed/31039742 http://dx.doi.org/10.1186/s12859-019-2792-7 |