Phenotypic screening of the ‘Kurz-box’ of chemicals identifies two compounds (BLK127 and HBK4) with anthelmintic activity in vitro against parasitic larval stages of Haemonchus contortus

BACKGROUND: Due to anthelmintic resistance problems, there is a need to discover and develop new drugs for the treatment and control of economically important and pathogenic nematodes of livestock animals. With this focus in mind, we screened 236 compounds from a library (called the ‘Kurz-box’) repr...

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Detalles Bibliográficos
Autores principales: Nguyen, Linh Thuy, Kurz, Thomas, Preston, Sarah, Brueckmann, Hjoerdis, Lungerich, Beate, Herath, H. M. P. Dilrukshi, Koehler, Anson V., Wang, Tao, Skálová, Lenka, Jabbar, Abdul, Gasser, Robin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492431/
https://www.ncbi.nlm.nih.gov/pubmed/31039802
http://dx.doi.org/10.1186/s13071-019-3426-7

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