A replication-incompetent CD154/40L recombinant vaccinia virus induces direct and macrophage-mediated antitumor effects in vitro and in vivo

CD40 triggering may result in antitumor effects of potentially high clinical relevance. To gain insights important for patient selection and to identify adequate targeting techniques, we investigated CD40 expression in human cancer tissues and generated a replication-incompetent recombinant vaccinia...

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Detalles Bibliográficos
Autores principales: Governa, Valeria, Brittoli, Alvaro, Mele, Valentina, Pinamonti, Maurizio, Terracciano, Luigi, Muenst, Simone, Iezzi, Giandomenica, Spagnoli, Giulio Cesare, Zajac, Paul, Trella, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492963/
https://www.ncbi.nlm.nih.gov/pubmed/31069131
http://dx.doi.org/10.1080/2162402X.2019.1568162

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