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Oncolytic viruses: how “lytic” must they be for therapeutic efficacy?
Oncolytic viruses (OVs) preferentially target and kill cancer cells without affecting healthy cells through a multi-modal mechanism of action. While historically the direct killing activity of OVs was considered the primary mode of action, initiation or augmentation of a host antitumor immune respon...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492965/ https://www.ncbi.nlm.nih.gov/pubmed/31069150 http://dx.doi.org/10.1080/2162402X.2019.1596006 |