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Acute Pulmonary Thromboembolism: 14 Years of Surgical Experience

BACKGROUND: Pulmonary thromboembolism (PTE) is a life-threatening disease with high mortality. This study aimed to assess the outcomes of surgical embolectomy and to clarify the sustained long-term effects of surgery by comparing preoperative, postoperative, and long-term follow-up echocardiography...

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Autores principales: Park, Jiye, Lim, Sang-Hyun, Hong, You Sun, Park, Soojin, Lee, Cheol Joo, Lee, Seung Ook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Thoracic and Cardiovascular Surgery 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493267/
https://www.ncbi.nlm.nih.gov/pubmed/31089444
http://dx.doi.org/10.5090/kjtcs.2019.52.2.78
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author Park, Jiye
Lim, Sang-Hyun
Hong, You Sun
Park, Soojin
Lee, Cheol Joo
Lee, Seung Ook
author_facet Park, Jiye
Lim, Sang-Hyun
Hong, You Sun
Park, Soojin
Lee, Cheol Joo
Lee, Seung Ook
author_sort Park, Jiye
collection PubMed
description BACKGROUND: Pulmonary thromboembolism (PTE) is a life-threatening disease with high mortality. This study aimed to assess the outcomes of surgical embolectomy and to clarify the sustained long-term effects of surgery by comparing preoperative, postoperative, and long-term follow-up echocardiography outcomes. Of 22 survivors, 21 were followed up for a mean (median) period of 6.8±5.4 years (4.2 years). METHODS: We retrospectively reviewed 27 surgical embolectomy cases for massive or submassive acute PTE from 2003 to 2016. Immediate and long-term follow-up outcomes of surgical embolectomy were assessed on the basis of 30-day mortality, long-term mortality, postoperative complications, right ventricular systolic pressure, and tricuspid regurgitation grade. RESULTS: The 30-day and long-term mortality rates were 14.8% (4 of 27) and 4.3% (1 of 23), respectively. Three patients had major postoperative complications, including hypoxic brain damage, acute kidney injury, and endobronchial bleeding, respectively (3.7% each). Right ventricular systolic pressure (median [range], mm Hg) decreased from 62.0 (45.5–78.5) to 31.0 (25.7–37.0, p<0.001). The tricuspid valve regurgitation grade (median [range]) decreased from 1.5 (0.63–2.00) to 0.50 (0.50–1.00, p<0.05). The improvement lasted until the last echocardiographic follow-up. CONCLUSION: Surgical embolectomy revealed favorable mortality and morbidity rates in patients with acute massive or submassive PTE, with sustained long-term improvements in cardiac function.
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spelling pubmed-64932672019-05-14 Acute Pulmonary Thromboembolism: 14 Years of Surgical Experience Park, Jiye Lim, Sang-Hyun Hong, You Sun Park, Soojin Lee, Cheol Joo Lee, Seung Ook Korean J Thorac Cardiovasc Surg Clinical Research BACKGROUND: Pulmonary thromboembolism (PTE) is a life-threatening disease with high mortality. This study aimed to assess the outcomes of surgical embolectomy and to clarify the sustained long-term effects of surgery by comparing preoperative, postoperative, and long-term follow-up echocardiography outcomes. Of 22 survivors, 21 were followed up for a mean (median) period of 6.8±5.4 years (4.2 years). METHODS: We retrospectively reviewed 27 surgical embolectomy cases for massive or submassive acute PTE from 2003 to 2016. Immediate and long-term follow-up outcomes of surgical embolectomy were assessed on the basis of 30-day mortality, long-term mortality, postoperative complications, right ventricular systolic pressure, and tricuspid regurgitation grade. RESULTS: The 30-day and long-term mortality rates were 14.8% (4 of 27) and 4.3% (1 of 23), respectively. Three patients had major postoperative complications, including hypoxic brain damage, acute kidney injury, and endobronchial bleeding, respectively (3.7% each). Right ventricular systolic pressure (median [range], mm Hg) decreased from 62.0 (45.5–78.5) to 31.0 (25.7–37.0, p<0.001). The tricuspid valve regurgitation grade (median [range]) decreased from 1.5 (0.63–2.00) to 0.50 (0.50–1.00, p<0.05). The improvement lasted until the last echocardiographic follow-up. CONCLUSION: Surgical embolectomy revealed favorable mortality and morbidity rates in patients with acute massive or submassive PTE, with sustained long-term improvements in cardiac function. The Korean Society for Thoracic and Cardiovascular Surgery 2019-04 2019-04-05 /pmc/articles/PMC6493267/ /pubmed/31089444 http://dx.doi.org/10.5090/kjtcs.2019.52.2.78 Text en Copyright © 2019 by The Korean Society for Thoracic and Cardiovascular Surgery. All rights Reserved. This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Research
Park, Jiye
Lim, Sang-Hyun
Hong, You Sun
Park, Soojin
Lee, Cheol Joo
Lee, Seung Ook
Acute Pulmonary Thromboembolism: 14 Years of Surgical Experience
title Acute Pulmonary Thromboembolism: 14 Years of Surgical Experience
title_full Acute Pulmonary Thromboembolism: 14 Years of Surgical Experience
title_fullStr Acute Pulmonary Thromboembolism: 14 Years of Surgical Experience
title_full_unstemmed Acute Pulmonary Thromboembolism: 14 Years of Surgical Experience
title_short Acute Pulmonary Thromboembolism: 14 Years of Surgical Experience
title_sort acute pulmonary thromboembolism: 14 years of surgical experience
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493267/
https://www.ncbi.nlm.nih.gov/pubmed/31089444
http://dx.doi.org/10.5090/kjtcs.2019.52.2.78
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