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Acute Pulmonary Thromboembolism: 14 Years of Surgical Experience
BACKGROUND: Pulmonary thromboembolism (PTE) is a life-threatening disease with high mortality. This study aimed to assess the outcomes of surgical embolectomy and to clarify the sustained long-term effects of surgery by comparing preoperative, postoperative, and long-term follow-up echocardiography...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society for Thoracic and Cardiovascular Surgery
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493267/ https://www.ncbi.nlm.nih.gov/pubmed/31089444 http://dx.doi.org/10.5090/kjtcs.2019.52.2.78 |
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author | Park, Jiye Lim, Sang-Hyun Hong, You Sun Park, Soojin Lee, Cheol Joo Lee, Seung Ook |
author_facet | Park, Jiye Lim, Sang-Hyun Hong, You Sun Park, Soojin Lee, Cheol Joo Lee, Seung Ook |
author_sort | Park, Jiye |
collection | PubMed |
description | BACKGROUND: Pulmonary thromboembolism (PTE) is a life-threatening disease with high mortality. This study aimed to assess the outcomes of surgical embolectomy and to clarify the sustained long-term effects of surgery by comparing preoperative, postoperative, and long-term follow-up echocardiography outcomes. Of 22 survivors, 21 were followed up for a mean (median) period of 6.8±5.4 years (4.2 years). METHODS: We retrospectively reviewed 27 surgical embolectomy cases for massive or submassive acute PTE from 2003 to 2016. Immediate and long-term follow-up outcomes of surgical embolectomy were assessed on the basis of 30-day mortality, long-term mortality, postoperative complications, right ventricular systolic pressure, and tricuspid regurgitation grade. RESULTS: The 30-day and long-term mortality rates were 14.8% (4 of 27) and 4.3% (1 of 23), respectively. Three patients had major postoperative complications, including hypoxic brain damage, acute kidney injury, and endobronchial bleeding, respectively (3.7% each). Right ventricular systolic pressure (median [range], mm Hg) decreased from 62.0 (45.5–78.5) to 31.0 (25.7–37.0, p<0.001). The tricuspid valve regurgitation grade (median [range]) decreased from 1.5 (0.63–2.00) to 0.50 (0.50–1.00, p<0.05). The improvement lasted until the last echocardiographic follow-up. CONCLUSION: Surgical embolectomy revealed favorable mortality and morbidity rates in patients with acute massive or submassive PTE, with sustained long-term improvements in cardiac function. |
format | Online Article Text |
id | pubmed-6493267 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The Korean Society for Thoracic and Cardiovascular Surgery |
record_format | MEDLINE/PubMed |
spelling | pubmed-64932672019-05-14 Acute Pulmonary Thromboembolism: 14 Years of Surgical Experience Park, Jiye Lim, Sang-Hyun Hong, You Sun Park, Soojin Lee, Cheol Joo Lee, Seung Ook Korean J Thorac Cardiovasc Surg Clinical Research BACKGROUND: Pulmonary thromboembolism (PTE) is a life-threatening disease with high mortality. This study aimed to assess the outcomes of surgical embolectomy and to clarify the sustained long-term effects of surgery by comparing preoperative, postoperative, and long-term follow-up echocardiography outcomes. Of 22 survivors, 21 were followed up for a mean (median) period of 6.8±5.4 years (4.2 years). METHODS: We retrospectively reviewed 27 surgical embolectomy cases for massive or submassive acute PTE from 2003 to 2016. Immediate and long-term follow-up outcomes of surgical embolectomy were assessed on the basis of 30-day mortality, long-term mortality, postoperative complications, right ventricular systolic pressure, and tricuspid regurgitation grade. RESULTS: The 30-day and long-term mortality rates were 14.8% (4 of 27) and 4.3% (1 of 23), respectively. Three patients had major postoperative complications, including hypoxic brain damage, acute kidney injury, and endobronchial bleeding, respectively (3.7% each). Right ventricular systolic pressure (median [range], mm Hg) decreased from 62.0 (45.5–78.5) to 31.0 (25.7–37.0, p<0.001). The tricuspid valve regurgitation grade (median [range]) decreased from 1.5 (0.63–2.00) to 0.50 (0.50–1.00, p<0.05). The improvement lasted until the last echocardiographic follow-up. CONCLUSION: Surgical embolectomy revealed favorable mortality and morbidity rates in patients with acute massive or submassive PTE, with sustained long-term improvements in cardiac function. The Korean Society for Thoracic and Cardiovascular Surgery 2019-04 2019-04-05 /pmc/articles/PMC6493267/ /pubmed/31089444 http://dx.doi.org/10.5090/kjtcs.2019.52.2.78 Text en Copyright © 2019 by The Korean Society for Thoracic and Cardiovascular Surgery. All rights Reserved. This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Research Park, Jiye Lim, Sang-Hyun Hong, You Sun Park, Soojin Lee, Cheol Joo Lee, Seung Ook Acute Pulmonary Thromboembolism: 14 Years of Surgical Experience |
title | Acute Pulmonary Thromboembolism: 14 Years of Surgical Experience |
title_full | Acute Pulmonary Thromboembolism: 14 Years of Surgical Experience |
title_fullStr | Acute Pulmonary Thromboembolism: 14 Years of Surgical Experience |
title_full_unstemmed | Acute Pulmonary Thromboembolism: 14 Years of Surgical Experience |
title_short | Acute Pulmonary Thromboembolism: 14 Years of Surgical Experience |
title_sort | acute pulmonary thromboembolism: 14 years of surgical experience |
topic | Clinical Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493267/ https://www.ncbi.nlm.nih.gov/pubmed/31089444 http://dx.doi.org/10.5090/kjtcs.2019.52.2.78 |
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