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Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach

The lung cancer stem cell (LuCSC) model comprises an attractive framework to explore acquired drug resistance in non-small cell lung cancer (NSCLC) treatment. Here, we used NSCLC cell line model to translate cellular heterogeneity into tractable populations to understand the origin of lung cancers a...

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Detalles Bibliográficos
Autores principales: Xiao, Zhiguang, Sperl, Bianca, Gärtner, Silvia, Nedelko, Tatiana, Stacher-Priehse, Elvira, Ullrich, Axel, Knyazev, Pjotr G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493460/
https://www.ncbi.nlm.nih.gov/pubmed/31069016
http://dx.doi.org/10.18632/oncotarget.26817