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Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors

Hepatitis A virus (HAV), an enigmatic and ancient pathogen, is a major causative agent of acute viral hepatitis worldwide. Although there are effective vaccines, antivirals against HAV infection are still required, especially during fulminant hepatitis outbreaks. A more in-depth understanding of the...

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Detalles Bibliográficos
Autores principales:	Cao, Lei, Liu, Pi, Yang, Pan, Gao, Qiang, Li, Hong, Sun, Yao, Zhu, Ling, Lin, Jianping, Su, Dan, Rao, Zihe, Wang, Xiangxi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493668/ https://www.ncbi.nlm.nih.gov/pubmed/31039149 http://dx.doi.org/10.1371/journal.pbio.3000229

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