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The Transcription Factor ERG Regulates Super-Enhancers Associated With an Endothelial-Specific Gene Expression Program
RATIONALE: The ETS (E-26 transformation-specific) transcription factor ERG (ETS-related gene) is essential for endothelial homeostasis, driving expression of lineage genes and repressing proinflammatory genes. Loss of ERG expression is associated with diseases including atherosclerosis. ERG’s homeos...
Autores principales: | Kalna, Viktoria, Yang, Youwen, Peghaire, Claire R., Frudd, Karen, Hannah, Rebecca, Shah, Aarti V., Osuna Almagro, Lourdes, Boyle, Joseph J., Göttgens, Berthold, Ferrer, Jorge, Randi, Anna M., Birdsey, Graeme M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493686/ https://www.ncbi.nlm.nih.gov/pubmed/30892142 http://dx.doi.org/10.1161/CIRCRESAHA.118.313788 |
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