Biological variation in the sizes, shapes and locations of visual cortical areas in the mouse

Visual cortex is organized into discrete sub-regions or areas that are arranged into a hierarchy and serves different functions in the processing of visual information. In retinotopic maps of mouse cortex, there appear to be substantial mouse-to-mouse differences in visual area location, size and sh...

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Detalles Bibliográficos
Autores principales: Waters, Jack, Lee, Eric, Gaudreault, Nathalie, Griffin, Fiona, Lecoq, Jerome, Slaughterbeck, Cliff, Sullivan, David, Farrell, Colin, Perkins, Jed, Reid, David, Feng, David, Graddis, Nile, Garrett, Marina, Li, Yang, Long, Fuhui, Mochizuki, Chris, Roll, Kate, Zhuang, Jun, Thompson, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493719/
https://www.ncbi.nlm.nih.gov/pubmed/31042712
http://dx.doi.org/10.1371/journal.pone.0213924
Descripción
Sumario:Visual cortex is organized into discrete sub-regions or areas that are arranged into a hierarchy and serves different functions in the processing of visual information. In retinotopic maps of mouse cortex, there appear to be substantial mouse-to-mouse differences in visual area location, size and shape. Here we quantify the biological variation in the size, shape and locations of 11 visual areas in the mouse, after separating biological variation and measurement noise. We find that there is biological variation in the locations and sizes of visual areas.

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