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Cryo-EM Structure of HER2-trastuzumab-pertuzumab complex

Trastuzumab and pertuzumab are monoclonal antibodies that bind to distinct subdomains of the extracellular domain of human epidermal growth factor receptor 2 (HER2). Adding these monoclonal antibodies to the treatment regimen of HER2-positive breast cancer has changed the paradigm for treatment in t...

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Detalles Bibliográficos
Autores principales:	Hao, Yue, Yu, Xinchao, Bai, Yonghong, McBride, Helen J., Huang, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493747/ https://www.ncbi.nlm.nih.gov/pubmed/31042744 http://dx.doi.org/10.1371/journal.pone.0216095

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