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Clinical course and risk factors of recurrent corneal erosion: Observational study
Recurrent corneal erosion (RCE) is a common disorder causing ocular pain, tearing, photophobia, and visual impairments. Various factors such as ocular trauma, ocular surgery, corneal dystrophy, contact lens wear, and diabetes mellitus (DM) can cause RCE. The purpose of this study was to determine th...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494251/ https://www.ncbi.nlm.nih.gov/pubmed/31008925 http://dx.doi.org/10.1097/MD.0000000000014964 |
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author | Nanba, Hisataka Mimura, Tatsuya Mizuno, Yoshinobu Matsumoto, Koichi Hamano, Shigeki Ubukata, Shoko Yamamoto, Megumi Watanabe, Emiko Mizota, Atsushi |
author_facet | Nanba, Hisataka Mimura, Tatsuya Mizuno, Yoshinobu Matsumoto, Koichi Hamano, Shigeki Ubukata, Shoko Yamamoto, Megumi Watanabe, Emiko Mizota, Atsushi |
author_sort | Nanba, Hisataka |
collection | PubMed |
description | Recurrent corneal erosion (RCE) is a common disorder causing ocular pain, tearing, photophobia, and visual impairments. Various factors such as ocular trauma, ocular surgery, corneal dystrophy, contact lens wear, and diabetes mellitus (DM) can cause RCE. The purpose of this study was to determine the causative factors and clinical course of RCE. We retrospectively examined 21 eyes of 21 patients with RCE and investigated the patients’ background, type of treatments, and clinical course after the treatments. All patients were treated with eye drops, ocular lubrication, or contact lens bandage for the RCE. Among the 21 patients with RCE, 9 were caused by trauma (Trauma group), 8 by DM (DM group), 1 by bacterial corneal ulcer, 1 by lagophthalmus and bacterial corneal ulcer, 1 by bandkeratopathy, and 1 by eyelid tumor (one eye). The mean age of the patients was 57.8 years with a range 34–91 years. The mean duration from the trauma to the onset of RCE was 5.2 ± 5.0 months (mean ± SD). The time required for a complete recovery of RCE was longer in the DM group (10.3 ± 3.1 weeks) than in the Trauma group (2.7 ± 1.1 weeks, P < .01). The presence of DM was significantly associated with the recovery duration of RCE (r = 0.72; P < .01). Multivariate analyses showed that the recovery duration of RCE was associated with the presence of DM (odds ratio = 139.8, P = .04). On the other hand, the type of treatments had no effect on the recovery duration of RCE. These findings suggest that trauma and DM are important causes of RCE. Wound recovery after RCE may be delayed in patients with DM. |
format | Online Article Text |
id | pubmed-6494251 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-64942512019-05-29 Clinical course and risk factors of recurrent corneal erosion: Observational study Nanba, Hisataka Mimura, Tatsuya Mizuno, Yoshinobu Matsumoto, Koichi Hamano, Shigeki Ubukata, Shoko Yamamoto, Megumi Watanabe, Emiko Mizota, Atsushi Medicine (Baltimore) Research Article Recurrent corneal erosion (RCE) is a common disorder causing ocular pain, tearing, photophobia, and visual impairments. Various factors such as ocular trauma, ocular surgery, corneal dystrophy, contact lens wear, and diabetes mellitus (DM) can cause RCE. The purpose of this study was to determine the causative factors and clinical course of RCE. We retrospectively examined 21 eyes of 21 patients with RCE and investigated the patients’ background, type of treatments, and clinical course after the treatments. All patients were treated with eye drops, ocular lubrication, or contact lens bandage for the RCE. Among the 21 patients with RCE, 9 were caused by trauma (Trauma group), 8 by DM (DM group), 1 by bacterial corneal ulcer, 1 by lagophthalmus and bacterial corneal ulcer, 1 by bandkeratopathy, and 1 by eyelid tumor (one eye). The mean age of the patients was 57.8 years with a range 34–91 years. The mean duration from the trauma to the onset of RCE was 5.2 ± 5.0 months (mean ± SD). The time required for a complete recovery of RCE was longer in the DM group (10.3 ± 3.1 weeks) than in the Trauma group (2.7 ± 1.1 weeks, P < .01). The presence of DM was significantly associated with the recovery duration of RCE (r = 0.72; P < .01). Multivariate analyses showed that the recovery duration of RCE was associated with the presence of DM (odds ratio = 139.8, P = .04). On the other hand, the type of treatments had no effect on the recovery duration of RCE. These findings suggest that trauma and DM are important causes of RCE. Wound recovery after RCE may be delayed in patients with DM. Wolters Kluwer Health 2019-04-19 /pmc/articles/PMC6494251/ /pubmed/31008925 http://dx.doi.org/10.1097/MD.0000000000014964 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 |
spellingShingle | Research Article Nanba, Hisataka Mimura, Tatsuya Mizuno, Yoshinobu Matsumoto, Koichi Hamano, Shigeki Ubukata, Shoko Yamamoto, Megumi Watanabe, Emiko Mizota, Atsushi Clinical course and risk factors of recurrent corneal erosion: Observational study |
title | Clinical course and risk factors of recurrent corneal erosion: Observational study |
title_full | Clinical course and risk factors of recurrent corneal erosion: Observational study |
title_fullStr | Clinical course and risk factors of recurrent corneal erosion: Observational study |
title_full_unstemmed | Clinical course and risk factors of recurrent corneal erosion: Observational study |
title_short | Clinical course and risk factors of recurrent corneal erosion: Observational study |
title_sort | clinical course and risk factors of recurrent corneal erosion: observational study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494251/ https://www.ncbi.nlm.nih.gov/pubmed/31008925 http://dx.doi.org/10.1097/MD.0000000000014964 |
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