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Environmental triggers for chronic cough

Cough is a physiological defense reflex for protecting the airways from aspiration and irritation. Thus, roles of environmental triggers are postulated in the pathogenesis of chronic cough. There are several lines of epidemiological evidence demonstrating the relationships between environmental irri...

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Detalles Bibliográficos
Autores principales: Jo, Eun-Jung, Song, Woo-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asia Pacific Association of Allergy, Asthma and Clinical Immunology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494656/
https://www.ncbi.nlm.nih.gov/pubmed/31089458
http://dx.doi.org/10.5415/apallergy.2019.9.e16
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author Jo, Eun-Jung
Song, Woo-Jung
author_facet Jo, Eun-Jung
Song, Woo-Jung
author_sort Jo, Eun-Jung
collection PubMed
description Cough is a physiological defense reflex for protecting the airways from aspiration and irritation. Thus, roles of environmental triggers are postulated in the pathogenesis of chronic cough. There are several lines of epidemiological evidence demonstrating the relationships between environmental irritant and pollutant exposure and chronic cough. However, positive findings from cross-sectional studies just reflect the protective nature of cough but may not properly address the true impact of environmental triggers. If harmful inhalation is repeated, cough may be seen as chronic but indeed is protective in nature. Therefore, long-term residual outcomes would be the key for understanding the effects of environmental triggers on chronic cough. The present review aims to summarize the associations between chronic cough and environmental pollutants or irritant exposure, with a focus on the long-term residual effects of (1) chronic persistent exposure and (2) acute high-intensity exposure on chronic cough, and also to examine (3) whether childhood irritant/pollutant exposure may increase the risk of chronic cough in adulthood.
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spelling pubmed-64946562019-05-14 Environmental triggers for chronic cough Jo, Eun-Jung Song, Woo-Jung Asia Pac Allergy Current Review Cough is a physiological defense reflex for protecting the airways from aspiration and irritation. Thus, roles of environmental triggers are postulated in the pathogenesis of chronic cough. There are several lines of epidemiological evidence demonstrating the relationships between environmental irritant and pollutant exposure and chronic cough. However, positive findings from cross-sectional studies just reflect the protective nature of cough but may not properly address the true impact of environmental triggers. If harmful inhalation is repeated, cough may be seen as chronic but indeed is protective in nature. Therefore, long-term residual outcomes would be the key for understanding the effects of environmental triggers on chronic cough. The present review aims to summarize the associations between chronic cough and environmental pollutants or irritant exposure, with a focus on the long-term residual effects of (1) chronic persistent exposure and (2) acute high-intensity exposure on chronic cough, and also to examine (3) whether childhood irritant/pollutant exposure may increase the risk of chronic cough in adulthood. Asia Pacific Association of Allergy, Asthma and Clinical Immunology 2019-04-20 /pmc/articles/PMC6494656/ /pubmed/31089458 http://dx.doi.org/10.5415/apallergy.2019.9.e16 Text en Copyright © 2019. Asia Pacific Association of Allergy, Asthma and Clinical Immunology. https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Current Review
Jo, Eun-Jung
Song, Woo-Jung
Environmental triggers for chronic cough
title Environmental triggers for chronic cough
title_full Environmental triggers for chronic cough
title_fullStr Environmental triggers for chronic cough
title_full_unstemmed Environmental triggers for chronic cough
title_short Environmental triggers for chronic cough
title_sort environmental triggers for chronic cough
topic Current Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494656/
https://www.ncbi.nlm.nih.gov/pubmed/31089458
http://dx.doi.org/10.5415/apallergy.2019.9.e16
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