Cargando…
A deeper insight into how GABA-B receptor agonism via baclofen may affect alcohol seeking and consumption: Lessons learned from a human laboratory investigation
Previous studies suggest that GABA-B receptor agonism may represent an effective pharmacological approach to treat addictive disorders. Baclofen is a selective GABA-B receptor agonist which has been investigated as a potential treatment for alcohol use disorder. However, research is needed to unders...
Autores principales: | Farokhnia, Mehdi, Deschaine, Sara L., Sadighi, Armin, Farinelli, Lisa A., Lee, Mary R., Akhlaghi, Fatemeh, Leggio, Lorenzo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494745/ https://www.ncbi.nlm.nih.gov/pubmed/30382188 http://dx.doi.org/10.1038/s41380-018-0287-y |
Ejemplares similares
-
Biobehavioral effects of baclofen in anxious alcohol-dependent individuals: a randomized, double-blind, placebo-controlled, laboratory study
por: Farokhnia, M, et al.
Publicado: (2017) -
Leptin Gene and Leptin Receptor Gene Polymorphisms in Alcohol Use Disorder: Findings Related to Psychopathology
por: Browning, Brittney D., et al.
Publicado: (2021) -
The novel ghrelin receptor inverse agonist PF-5190457 administered with alcohol: preclinical safety experiments and a phase 1b human laboratory study
por: Lee, Mary R., et al.
Publicado: (2018) -
GABA(B)-Agonistic Activity of Certain Baclofen Homologues
por: Attia, Mohamed I., et al.
Publicado: (2013) -
Increased Ethanol Consumption Following Chronic Psychosocial Stress: Do Oxytocin and Baclofen Hold any Therapeutic Promise?
por: Lee, Mary R., et al.
Publicado: (2013)