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Mycobacterium tuberculosis ESAT6 Drives the Activation and Maturation of Bone Marrow-Derived Dendritic Cells via TLR4-Mediated Signaling

6-kDa early secretory antigenic target (ESAT6), a virulent factor of Mycobacterium tuberculosis, is involved in immune regulation. However, the underlying mechanism behind the activation and maturation of dendritic cells (DCs) by ESAT6 remains unclear. In this study, we investigated the effect on TL...

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Detalles Bibliográficos
Autores principales: Jang, Ah-Ra, Kim, Green, Hong, Jung Joo, Kang, Soon Myung, Shin, Sung Jae, Park, Jong-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494767/
https://www.ncbi.nlm.nih.gov/pubmed/31089440
http://dx.doi.org/10.4110/in.2019.19.e13