Metabolic Reprogramming by the Excessive AMPK Activation Exacerbates Antigen-Specific Memory CD8(+) T Cell Differentiation after Acute Lymphocytic Choriomeningitis Virus Infection

During virus infection, T cells must be adapted to activation and lineage differentiation states via metabolic reprogramming. Whereas effector CD8(+) T cells preferentially use glycolysis for their rapid proliferation, memory CD8(+) T cells utilize oxidative phosphorylation for their homeostatic mai...

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Detalles Bibliográficos
Autores principales: Son, Jimin, Cho, Yong Woo, Woo, Youn Jung, Baek, Young Ae, Kim, Eun Jee, Cho, Yuri, Kim, Joon Ye, Kim, Beom Seok, Song, Jason Jungsik, Ha, Sang-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494768/
https://www.ncbi.nlm.nih.gov/pubmed/31089438
http://dx.doi.org/10.4110/in.2019.19.e11

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