Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors

Capicua (Cic) is a transcriptional repressor mutated in the brain cancer oligodendroglioma. Despite its cancer link, little is known of Cic’s function in the brain. We show that nuclear Cic expression is strongest in astrocytes and neurons but weaker in stem cells and oligodendroglial lineage cells....

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Detalles Bibliográficos
Autores principales: Ahmad, Shiekh Tanveer, Rogers, Alexandra D., Chen, Myra J., Dixit, Rajiv, Adnani, Lata, Frankiw, Luke S., Lawn, Samuel O., Blough, Michael D., Alshehri, Mana, Wu, Wei, Marra, Marco A., Robbins, Stephen M., Cairncross, J. Gregory, Schuurmans, Carol, Chan, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494820/
https://www.ncbi.nlm.nih.gov/pubmed/31043608
http://dx.doi.org/10.1038/s41467-019-09949-6

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