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Drug-like Fragments Inhibit agr-Mediated Virulence Expression in Staphylococcus aureus

In response to the increasingly problematic emergence of antibiotic resistance, novel strategies for combating pathogenic bacteria are being investigated. Targeting the agr quorum sensing system, which regulates expression of virulence in Staphylococcus aureus, is one potentially useful approach for...

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Detalles Bibliográficos
Autores principales:	Bezar, Ian F., Mashruwala, Ameya A., Boyd, Jeffrey M., Stock, Ann M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494831/ https://www.ncbi.nlm.nih.gov/pubmed/31043623 http://dx.doi.org/10.1038/s41598-019-42853-z

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