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High mitogenic stimulation arrests angiogenesis
Appropriate therapeutic modulation of endothelial proliferation and sprouting is essential for the effective inhibition of angiogenesis in cancer or its induction in cardiovascular disease. The current view is that an increase in growth factor concentration, and the resulting mitogenic activity, inc...
Autores principales: | Pontes-Quero, Samuel, Fernández-Chacón, Macarena, Luo, Wen, Lunella, Federica Francesca, Casquero-Garcia, Verónica, Garcia-Gonzalez, Irene, Hermoso, Ana, Rocha, Susana F., Bansal, Mayank, Benedito, Rui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494832/ https://www.ncbi.nlm.nih.gov/pubmed/31043605 http://dx.doi.org/10.1038/s41467-019-09875-7 |
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