Phosphodiesterase 5 inhibition improves contractile function and restores transverse tubule loss and catecholamine responsiveness in heart failure

Heart failure (HF) is characterized by poor survival, a loss of catecholamine reserve and cellular structural remodeling in the form of disorganization and loss of the transverse tubule network. Indeed, survival rates for HF are worse than many common cancers and have not improved over time. Tadalaf...

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Detalles Bibliográficos
Autores principales: Lawless, Michael, Caldwell, Jessica L., Radcliffe, Emma J., Smith, Charlotte E. R., Madders, George W. P., Hutchings, David C., Woods, Lori S., Church, Stephanie J., Unwin, Richard D., Kirkwood, Graeme J., Becker, Lorenz K., Pearman, Charles M., Taylor, Rebecca F., Eisner, David A., Dibb, Katharine M., Trafford, Andrew. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494852/
https://www.ncbi.nlm.nih.gov/pubmed/31043634
http://dx.doi.org/10.1038/s41598-019-42592-1

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