Automated four-dimensional long term imaging enables single cell tracking within organotypic brain slices to study neurodevelopment and degeneration

Current approaches for dynamic profiling of single cells rely on dissociated cultures, which lack important biological features existing in tissues. Organotypic slice cultures preserve aspects of structural and synaptic organisation within the brain and are amenable to microscopy, but established te...

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Detalles Bibliográficos
Autores principales: Linsley, Jeremy W., Tripathi, Atmiyata, Epstein, Irina, Schmunk, Galina, Mount, Elliot, Campioni, Matthew, Oza, Viral, Barch, Mariya, Javaherian, Ashkan, Nowakowski, Tomasz J., Samsi, Siddharth, Finkbeiner, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494885/
https://www.ncbi.nlm.nih.gov/pubmed/31069265
http://dx.doi.org/10.1038/s42003-019-0411-9

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