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Association Between Changes in BLyS Levels and the Composition of B and T Cell Compartments in Patients With Refractory Systemic Lupus Erythematosus Treated With Belimumab
Introduction: Belimumab is a monoclonal antibody against soluble BLyS used for treatment of refractory Systemic Lupus Erythematosus (SLE). Although B cells are the main target of this therapy, a BLyS-dependent T cell activation pathway has also been demonstrated. The aim of the study is to analyze B...
Autores principales: | Regola, Francesca, Piantoni, Silvia, Lowin, Torsten, Archetti, Silvia, Reggia, Rossella, Kumar, Rajesh, Franceschini, Franco, Airò, Paolo, Tincani, Angela, Andreoli, Laura, Pongratz, Georg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494924/ https://www.ncbi.nlm.nih.gov/pubmed/31105569 http://dx.doi.org/10.3389/fphar.2019.00433 |
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