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Exhaled Breath Condensate in Childhood Asthma: A Review and Current Perspective
Exhaled breath condensate (EBC) was introduced more than two decades ago as a novel, non-invasive tool to assess airway inflammation. This review summarizes the latest literature on the various markers in EBC to predict asthma in children. Despite many recommendations and two comprehensive Task Forc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494934/ https://www.ncbi.nlm.nih.gov/pubmed/31106182 http://dx.doi.org/10.3389/fped.2019.00150 |
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author | Bannier, Michiel A. G. E. Rosias, Philippe P. R. Jöbsis, Quirijn Dompeling, Edward |
author_facet | Bannier, Michiel A. G. E. Rosias, Philippe P. R. Jöbsis, Quirijn Dompeling, Edward |
author_sort | Bannier, Michiel A. G. E. |
collection | PubMed |
description | Exhaled breath condensate (EBC) was introduced more than two decades ago as a novel, non-invasive tool to assess airway inflammation. This review summarizes the latest literature on the various markers in EBC to predict asthma in children. Despite many recommendations and two comprehensive Task Force reports, there is still large heterogeneity in published data. The biggest issue remains a lack of standardization regarding EBC collection, preservation, processing, and analysis. As a result, published studies show mixed or conflicting results, questioning the reproducibility of findings. A joint, multicenter research study is urgently needed to address the necessary methodological standardization. |
format | Online Article Text |
id | pubmed-6494934 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-64949342019-05-17 Exhaled Breath Condensate in Childhood Asthma: A Review and Current Perspective Bannier, Michiel A. G. E. Rosias, Philippe P. R. Jöbsis, Quirijn Dompeling, Edward Front Pediatr Pediatrics Exhaled breath condensate (EBC) was introduced more than two decades ago as a novel, non-invasive tool to assess airway inflammation. This review summarizes the latest literature on the various markers in EBC to predict asthma in children. Despite many recommendations and two comprehensive Task Force reports, there is still large heterogeneity in published data. The biggest issue remains a lack of standardization regarding EBC collection, preservation, processing, and analysis. As a result, published studies show mixed or conflicting results, questioning the reproducibility of findings. A joint, multicenter research study is urgently needed to address the necessary methodological standardization. Frontiers Media S.A. 2019-04-25 /pmc/articles/PMC6494934/ /pubmed/31106182 http://dx.doi.org/10.3389/fped.2019.00150 Text en Copyright © 2019 Bannier, Rosias, Jöbsis and Dompeling. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pediatrics Bannier, Michiel A. G. E. Rosias, Philippe P. R. Jöbsis, Quirijn Dompeling, Edward Exhaled Breath Condensate in Childhood Asthma: A Review and Current Perspective |
title | Exhaled Breath Condensate in Childhood Asthma: A Review and Current Perspective |
title_full | Exhaled Breath Condensate in Childhood Asthma: A Review and Current Perspective |
title_fullStr | Exhaled Breath Condensate in Childhood Asthma: A Review and Current Perspective |
title_full_unstemmed | Exhaled Breath Condensate in Childhood Asthma: A Review and Current Perspective |
title_short | Exhaled Breath Condensate in Childhood Asthma: A Review and Current Perspective |
title_sort | exhaled breath condensate in childhood asthma: a review and current perspective |
topic | Pediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494934/ https://www.ncbi.nlm.nih.gov/pubmed/31106182 http://dx.doi.org/10.3389/fped.2019.00150 |
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