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Electrospraying: Possibilities and Challenges of Engineering Carriers for Biomedical Applications—A Mini Review

Electrospraying, a liquid atomization-based technique, has been used to produce and formulate micro/nanoparticular cargo carriers for various biomedical applications, including drug delivery, biomedical imaging, implant coatings, and tissue engineering. In this mini review, we begin with the main fe...

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Detalles Bibliográficos
Autores principales: Wang, Jiamian, Jansen, John A., Yang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494963/
https://www.ncbi.nlm.nih.gov/pubmed/31106194
http://dx.doi.org/10.3389/fchem.2019.00258
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author Wang, Jiamian
Jansen, John A.
Yang, Fang
author_facet Wang, Jiamian
Jansen, John A.
Yang, Fang
author_sort Wang, Jiamian
collection PubMed
description Electrospraying, a liquid atomization-based technique, has been used to produce and formulate micro/nanoparticular cargo carriers for various biomedical applications, including drug delivery, biomedical imaging, implant coatings, and tissue engineering. In this mini review, we begin with the main features of electrospraying methods to engineer carriers with various bioactive cargos, including genes, growth factors, and enzymes. In particular, this review focuses on the improvement of traditional electrospraying technology for the fabrication of carriers for living cells and providing a suitable condition for gene transformation. Subsequently, the major applications of the electrosprayed carriers in the biomedical field are highlighted. Finally, we finish with conclusions and future perspectives of electrospraying for high efficiency and safe production.
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spelling pubmed-64949632019-05-17 Electrospraying: Possibilities and Challenges of Engineering Carriers for Biomedical Applications—A Mini Review Wang, Jiamian Jansen, John A. Yang, Fang Front Chem Chemistry Electrospraying, a liquid atomization-based technique, has been used to produce and formulate micro/nanoparticular cargo carriers for various biomedical applications, including drug delivery, biomedical imaging, implant coatings, and tissue engineering. In this mini review, we begin with the main features of electrospraying methods to engineer carriers with various bioactive cargos, including genes, growth factors, and enzymes. In particular, this review focuses on the improvement of traditional electrospraying technology for the fabrication of carriers for living cells and providing a suitable condition for gene transformation. Subsequently, the major applications of the electrosprayed carriers in the biomedical field are highlighted. Finally, we finish with conclusions and future perspectives of electrospraying for high efficiency and safe production. Frontiers Media S.A. 2019-04-25 /pmc/articles/PMC6494963/ /pubmed/31106194 http://dx.doi.org/10.3389/fchem.2019.00258 Text en Copyright © 2019 Wang, Jansen and Yang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Wang, Jiamian
Jansen, John A.
Yang, Fang
Electrospraying: Possibilities and Challenges of Engineering Carriers for Biomedical Applications—A Mini Review
title Electrospraying: Possibilities and Challenges of Engineering Carriers for Biomedical Applications—A Mini Review
title_full Electrospraying: Possibilities and Challenges of Engineering Carriers for Biomedical Applications—A Mini Review
title_fullStr Electrospraying: Possibilities and Challenges of Engineering Carriers for Biomedical Applications—A Mini Review
title_full_unstemmed Electrospraying: Possibilities and Challenges of Engineering Carriers for Biomedical Applications—A Mini Review
title_short Electrospraying: Possibilities and Challenges of Engineering Carriers for Biomedical Applications—A Mini Review
title_sort electrospraying: possibilities and challenges of engineering carriers for biomedical applications—a mini review
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494963/
https://www.ncbi.nlm.nih.gov/pubmed/31106194
http://dx.doi.org/10.3389/fchem.2019.00258
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