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Electrospraying: Possibilities and Challenges of Engineering Carriers for Biomedical Applications—A Mini Review
Electrospraying, a liquid atomization-based technique, has been used to produce and formulate micro/nanoparticular cargo carriers for various biomedical applications, including drug delivery, biomedical imaging, implant coatings, and tissue engineering. In this mini review, we begin with the main fe...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494963/ https://www.ncbi.nlm.nih.gov/pubmed/31106194 http://dx.doi.org/10.3389/fchem.2019.00258 |
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author | Wang, Jiamian Jansen, John A. Yang, Fang |
author_facet | Wang, Jiamian Jansen, John A. Yang, Fang |
author_sort | Wang, Jiamian |
collection | PubMed |
description | Electrospraying, a liquid atomization-based technique, has been used to produce and formulate micro/nanoparticular cargo carriers for various biomedical applications, including drug delivery, biomedical imaging, implant coatings, and tissue engineering. In this mini review, we begin with the main features of electrospraying methods to engineer carriers with various bioactive cargos, including genes, growth factors, and enzymes. In particular, this review focuses on the improvement of traditional electrospraying technology for the fabrication of carriers for living cells and providing a suitable condition for gene transformation. Subsequently, the major applications of the electrosprayed carriers in the biomedical field are highlighted. Finally, we finish with conclusions and future perspectives of electrospraying for high efficiency and safe production. |
format | Online Article Text |
id | pubmed-6494963 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-64949632019-05-17 Electrospraying: Possibilities and Challenges of Engineering Carriers for Biomedical Applications—A Mini Review Wang, Jiamian Jansen, John A. Yang, Fang Front Chem Chemistry Electrospraying, a liquid atomization-based technique, has been used to produce and formulate micro/nanoparticular cargo carriers for various biomedical applications, including drug delivery, biomedical imaging, implant coatings, and tissue engineering. In this mini review, we begin with the main features of electrospraying methods to engineer carriers with various bioactive cargos, including genes, growth factors, and enzymes. In particular, this review focuses on the improvement of traditional electrospraying technology for the fabrication of carriers for living cells and providing a suitable condition for gene transformation. Subsequently, the major applications of the electrosprayed carriers in the biomedical field are highlighted. Finally, we finish with conclusions and future perspectives of electrospraying for high efficiency and safe production. Frontiers Media S.A. 2019-04-25 /pmc/articles/PMC6494963/ /pubmed/31106194 http://dx.doi.org/10.3389/fchem.2019.00258 Text en Copyright © 2019 Wang, Jansen and Yang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Chemistry Wang, Jiamian Jansen, John A. Yang, Fang Electrospraying: Possibilities and Challenges of Engineering Carriers for Biomedical Applications—A Mini Review |
title | Electrospraying: Possibilities and Challenges of Engineering Carriers for Biomedical Applications—A Mini Review |
title_full | Electrospraying: Possibilities and Challenges of Engineering Carriers for Biomedical Applications—A Mini Review |
title_fullStr | Electrospraying: Possibilities and Challenges of Engineering Carriers for Biomedical Applications—A Mini Review |
title_full_unstemmed | Electrospraying: Possibilities and Challenges of Engineering Carriers for Biomedical Applications—A Mini Review |
title_short | Electrospraying: Possibilities and Challenges of Engineering Carriers for Biomedical Applications—A Mini Review |
title_sort | electrospraying: possibilities and challenges of engineering carriers for biomedical applications—a mini review |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494963/ https://www.ncbi.nlm.nih.gov/pubmed/31106194 http://dx.doi.org/10.3389/fchem.2019.00258 |
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