Cargando…

Characterizing ABC-Transporter Substrate-Likeness Using a Clean-Slate Genetic Background

Mutations in ATP Binding Cassette (ABC)-transporter genes can have major effects on the bioavailability and toxicity of the drugs that are ABC-transporter substrates. Consequently, methods to predict if a drug is an ABC-transporter substrate are useful for drug development. Such methods traditionall...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sokolov, Artem, Ashenden, Stephanie, Sahin, Nil, Lewis, Richard, Erdem, Nurdan, Ozaltan, Elif, Bender, Andreas, Roth, Frederick P., Cokol, Murat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494965/ https://www.ncbi.nlm.nih.gov/pubmed/31105571 http://dx.doi.org/10.3389/fphar.2019.00448

Ejemplares similares

Wiping the cellular slate clean
por: Wells, William A.
Publicado: (2005)

A clean slate approach to secure wireless networking
por: Ponniah, Jonathan, et al.
Publicado: (2015)

Guided screen for synergistic three-drug combinations
por: Cokol-Cakmak, Melike, et al.
Publicado: (2020)

The Slate Garden
por: Alexandre Pelletier and Anaïs Schaeffer
Publicado: (2011)

Nuclear research slated for Geneva
por: Williams, O
Publicado: (1955)

LHC slated for September restart
Publicado: (2009)

Fannin & Co.'s Clinical Slate
Publicado: (1891)

Laser Microdrilling of Slate Tiles
por: Penide, Joaquín, et al.
Publicado: (2019)

Hand Washing Induces a Clean Slate Effect in Moral Judgments: A Pupillometry and Eye-Tracking Study
por: Kaspar, Kai, et al.
Publicado: (2015)

Chemogenomics and orthology‐based design of antibiotic combination therapies
por: Chandrasekaran, Sriram, et al.
Publicado: (2016)

The blank slate: the modern denial of human nature
por: Pinker, Steven
Publicado: (2019)

Biochemical studies on the toxicity of slate mine dust.
por: Khan, M F, et al.
Publicado: (1983)

Large Hadron Collider slated to restart operation
Publicado: (2009)

Nuclear research center slated soon near Geneva
por: Bakker, Cornelis Jan, et al.
Publicado: (1954)

SLATE on-line program for trigger and DAQ test systems
por: Dénes, E, et al.
Publicado: (1996)

Earliest LHC restart slated for late summer 2009
Publicado: (2008)

Large Hadron Collider slated to restart operation in September
Publicado: (2009)

Lithotomy; Removal of a Slate Pencil from the Bladder
por: Baillie, Herbert
Publicado: (1867)

India slated for using facial recognition in virus battle
Publicado: (2021)

A blank slate – apropos a clinical case
por: Ramos, S. Freitas, et al.
Publicado: (2021)

Twenty-fifth Annual Meeting of the Ohio Slate Dental Society
por: Arnold, Otto
Publicado: (1892)

Hydrothermal Extraction of Amorphous Silica from Locally Available Slate
por: Ghani, Usman, et al.
Publicado: (2022)

Duality of the Brain—A Theory of Mind-Reading and Slate-Writing
por: Word, R. C.
Publicado: (1888)

Clearing the slate: RNA turnover to enable cell state switching?
por: Westbrook, Elizabeth R., et al.
Publicado: (2023)

Modeling the impact of drug interactions on therapeutic selectivity
por: Weinstein, Zohar B., et al.
Publicado: (2018)

Efficient measurement and factorization of high-order drug interactions in Mycobacterium tuberculosis
por: Cokol, Murat, et al.
Publicado: (2017)

Study on Failure Mechanism and Numerical Simulation of Argillaceous Slate in Southeastern Guizhou
por: Zhang, Jinfeng, et al.
Publicado: (2023)

Investigation of Damage and Creep for Bedding’s Carbonaceous Slate with Chemical Erosion Effect
por: Zeng, Weihao, et al.
Publicado: (2023)

Medical students are not blank slates: Positionality and curriculum interact to develop professional identity
por: Fergus, Kirkpatrick B., et al.
Publicado: (2018)

Enzymatic Bioweathering and Metal Mobilization From Black Slate by the Basidiomycete Schizophyllum commune
por: Kirtzel, Julia, et al.
Publicado: (2018)

Calculation method of HJC constitutive model parameters of natural joint angle slate
por: Wan, Antong, et al.
Publicado: (2023)

The LHC magnet cleaning system (in the background) for cleaning the magnet vacuum chambers before installation
por: Laurent Guiraud
Publicado: (2000)

Sequestration of Anionic and Cationic Dyes through Thermally Activated Slate and Their Kinetics and Thermodynamic Characteristics
por: Hussain, Shah, et al.
Publicado: (2022)

Comparison of Slate Safety Wearable Device to Ingestible Pill and Wearable Heart Rate Monitor
por: Callihan, Michael, et al.
Publicado: (2023)

Construction of Asbestos Slate Deep-Learning Training-Data Model Based on Drone Images
por: Baek, Seung-Chan, et al.
Publicado: (2023)

The Mechanical Performance of Recycled Slate Waste Fiber Composites Based on Unsaturated Polyester Resins
por: Ruiz-Bustos, Rocío, et al.
Publicado: (2023)

Diagonal Method to Measure Synergy Among Any Number of Drugs
por: Cokol-Cakmak, Melike, et al.
Publicado: (2018)

Modification Tests to Optimize Highway Construction in Crown of Slate Random Embankments with Compaction Quality Control
por: Teijón-López-Zuazo, Evelio, et al.
Publicado: (2020)

Asbestos Exposure Level and the Carcinogenic Risk Due to Corrugated Asbestos-Cement Slate Roofs in Korea
por: Lee, Eun-Soo, et al.
Publicado: (2021)

Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter
por: Chaptal, Vincent, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ud1nlnv5rdb69il9o8qf3jvc90