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Comparison of Sexual Function and Serum Testosterone Levels in Men Opiate Addicts, under Methadone Maintenance Therapy, and Healthy Men
BACKGROUND: Substance abuse and consequently the use of methadone in Iran are reported at high levels. Drugs alter sexual function by affecting the organs of the body. The aim of this study was to evaluate sexual functioning and serum testosterone levels in opiate addicts, individuals receiving meth...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kerman University of Medical Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494984/ https://www.ncbi.nlm.nih.gov/pubmed/31069031 http://dx.doi.org/10.22122/ahj.v10i2.540 |
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author | Agha-Mohammadhasani, Parvin Mokhtaree, Mohammadreza Nazari, Alireza Rahnama, Amir |
author_facet | Agha-Mohammadhasani, Parvin Mokhtaree, Mohammadreza Nazari, Alireza Rahnama, Amir |
author_sort | Agha-Mohammadhasani, Parvin |
collection | PubMed |
description | BACKGROUND: Substance abuse and consequently the use of methadone in Iran are reported at high levels. Drugs alter sexual function by affecting the organs of the body. The aim of this study was to evaluate sexual functioning and serum testosterone levels in opiate addicts, individuals receiving methadone maintenance treatment (MMT), and healthy men living in the city of Rafsanjan, Iran, in 2016. METHODS: The statistical population of this descriptive study included: A) opium-smoking men, B) individuals undergoing MMT, and C) those without any history of substance abuse. Using a formula, the sample size consisted of 70 individuals who were randomly selected from the statistical population. The study samples also completed the International Index of Erectile Function (IIEF). Moreover, the serum testosterone levels were measured using the laboratory-based Enzyme Linked Immunosorbent Assay (ELISA) diagnostic kits. The data were analyzed by SPSS software using Mann-Whitney U and Kruskal-Wallis tests with a significant level of < 0.050. FINDINGS: The serum testosterone levels in healthy individuals were higher than those in other two groups (P = 0.001). In addition, the sexual functioning indicators of men receiving MMT and opiate-smoking ones (P = 0.001) were lower than those of healthy individuals except for overall sexual satisfaction (P = 0.069). CONCLUSION: Methadone and opium reduce different aspects of sexual functioning. It seems that this change was through having impacts on serum testosterone levels; however, psychological, social, and economic dimensions are suggested to be considered in this domain. |
format | Online Article Text |
id | pubmed-6494984 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Kerman University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-64949842019-05-08 Comparison of Sexual Function and Serum Testosterone Levels in Men Opiate Addicts, under Methadone Maintenance Therapy, and Healthy Men Agha-Mohammadhasani, Parvin Mokhtaree, Mohammadreza Nazari, Alireza Rahnama, Amir Addict Health Original Article BACKGROUND: Substance abuse and consequently the use of methadone in Iran are reported at high levels. Drugs alter sexual function by affecting the organs of the body. The aim of this study was to evaluate sexual functioning and serum testosterone levels in opiate addicts, individuals receiving methadone maintenance treatment (MMT), and healthy men living in the city of Rafsanjan, Iran, in 2016. METHODS: The statistical population of this descriptive study included: A) opium-smoking men, B) individuals undergoing MMT, and C) those without any history of substance abuse. Using a formula, the sample size consisted of 70 individuals who were randomly selected from the statistical population. The study samples also completed the International Index of Erectile Function (IIEF). Moreover, the serum testosterone levels were measured using the laboratory-based Enzyme Linked Immunosorbent Assay (ELISA) diagnostic kits. The data were analyzed by SPSS software using Mann-Whitney U and Kruskal-Wallis tests with a significant level of < 0.050. FINDINGS: The serum testosterone levels in healthy individuals were higher than those in other two groups (P = 0.001). In addition, the sexual functioning indicators of men receiving MMT and opiate-smoking ones (P = 0.001) were lower than those of healthy individuals except for overall sexual satisfaction (P = 0.069). CONCLUSION: Methadone and opium reduce different aspects of sexual functioning. It seems that this change was through having impacts on serum testosterone levels; however, psychological, social, and economic dimensions are suggested to be considered in this domain. Kerman University of Medical Sciences 2018-04 /pmc/articles/PMC6494984/ /pubmed/31069031 http://dx.doi.org/10.22122/ahj.v10i2.540 Text en © 2018 Kerman University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. |
spellingShingle | Original Article Agha-Mohammadhasani, Parvin Mokhtaree, Mohammadreza Nazari, Alireza Rahnama, Amir Comparison of Sexual Function and Serum Testosterone Levels in Men Opiate Addicts, under Methadone Maintenance Therapy, and Healthy Men |
title | Comparison of Sexual Function and Serum Testosterone Levels in Men Opiate Addicts, under Methadone Maintenance Therapy, and Healthy Men |
title_full | Comparison of Sexual Function and Serum Testosterone Levels in Men Opiate Addicts, under Methadone Maintenance Therapy, and Healthy Men |
title_fullStr | Comparison of Sexual Function and Serum Testosterone Levels in Men Opiate Addicts, under Methadone Maintenance Therapy, and Healthy Men |
title_full_unstemmed | Comparison of Sexual Function and Serum Testosterone Levels in Men Opiate Addicts, under Methadone Maintenance Therapy, and Healthy Men |
title_short | Comparison of Sexual Function and Serum Testosterone Levels in Men Opiate Addicts, under Methadone Maintenance Therapy, and Healthy Men |
title_sort | comparison of sexual function and serum testosterone levels in men opiate addicts, under methadone maintenance therapy, and healthy men |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494984/ https://www.ncbi.nlm.nih.gov/pubmed/31069031 http://dx.doi.org/10.22122/ahj.v10i2.540 |
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