A Novel Chimeric Poxvirus Encoding hNIS Is Tumor-Tropic, Imageable, and Synergistic with Radioiodine to Sustain Colon Cancer Regression

Colon cancer has a high rate of recurrence even with good response to modern therapies. Novel curative adjuncts are needed. Oncolytic viral therapy has shown preclinical promise against colon cancer but lacks robust efficacy in clinical trials and raises regulatory concerns without real-time trackin...

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Detalles Bibliográficos
Autores principales: Warner, Susanne G., Kim, Sang-In, Chaurasiya, Shyambabu, O’Leary, Michael P., Lu, Jianming, Sivanandam, Venkatesh, Woo, Yanghee, Chen, Nanhai G., Fong, Yuman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495072/
https://www.ncbi.nlm.nih.gov/pubmed/31061881
http://dx.doi.org/10.1016/j.omto.2019.04.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495072/
https://www.ncbi.nlm.nih.gov/pubmed/31061881
http://dx.doi.org/10.1016/j.omto.2019.04.001

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