Reiterative Synthesis by the Ribosome and Recognition of the N-Terminal Formyl Group by Biosynthetic Machinery Contribute to Evolutionary Conservation of the Length of Antibiotic Microcin C Peptide Precursor

Microcin C (McC) is a peptide adenylate antibiotic produced by Escherichiacoli cells bearing a plasmid-borne mcc gene cluster. Most MccA precursors, encoded by validated mcc operons from diverse bacteria, are 7 amino acids long, but the significance of this precursor length conservation has remained...

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Detalles Bibliográficos
Autores principales: Zukher, Inna, Pavlov, Michael, Tsibulskaya, Darya, Kulikovsky, Alexey, Zyubko, Tatyana, Bikmetov, Dmitry, Serebryakova, Marina, Nair, Satish K., Ehrenberg, Måns, Dubiley, Svetlana, Severinov, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495379/
https://www.ncbi.nlm.nih.gov/pubmed/31040244
http://dx.doi.org/10.1128/mBio.00768-19

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