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Control of Klebsiella pneumoniae Infection in Mice by Using Dissolving Microarray Patches Containing Gentamicin

Using a murine model of Klebsiella pneumoniae bacterial infection, we demonstrate that gentamicin dissolving microarray patches, applied to murine ears, could control K. pneumoniae infection. Mice treated with microarray patches had reduced bacterial burden in the nasal-associated lymphoid tissue an...

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Detalles Bibliográficos
Autores principales: Rodgers, Aoife M., McCrudden, Maelíosa T. C., Courtenay, Aaron J., Kearney, Mary-Carmel, Edwards, Katherine L., Ingram, Rebecca J., Bengoechea, Jose, Donnelly, Ryan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496091/
https://www.ncbi.nlm.nih.gov/pubmed/30858214
http://dx.doi.org/10.1128/AAC.02612-18