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Control of Klebsiella pneumoniae Infection in Mice by Using Dissolving Microarray Patches Containing Gentamicin
Using a murine model of Klebsiella pneumoniae bacterial infection, we demonstrate that gentamicin dissolving microarray patches, applied to murine ears, could control K. pneumoniae infection. Mice treated with microarray patches had reduced bacterial burden in the nasal-associated lymphoid tissue an...
Autores principales: | Rodgers, Aoife M., McCrudden, Maelíosa T. C., Courtenay, Aaron J., Kearney, Mary-Carmel, Edwards, Katherine L., Ingram, Rebecca J., Bengoechea, Jose, Donnelly, Ryan F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496091/ https://www.ncbi.nlm.nih.gov/pubmed/30858214 http://dx.doi.org/10.1128/AAC.02612-18 |
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