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Blockage of SLC31A1‐dependent copper absorption increases pancreatic cancer cell autophagy to resist cell death
OBJECTIVES: Clinical observations have demonstrated that copper levels elevate in several cancer types, and copper deprivation is shown to inhibit tumour angiogenesis and growth in both animal models and preclinical trials. However, the content of copper in pancreatic duct adenocarcinoma (PDAC) and...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496122/ https://www.ncbi.nlm.nih.gov/pubmed/30706544 http://dx.doi.org/10.1111/cpr.12568 |