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Blockage of SLC31A1‐dependent copper absorption increases pancreatic cancer cell autophagy to resist cell death

OBJECTIVES: Clinical observations have demonstrated that copper levels elevate in several cancer types, and copper deprivation is shown to inhibit tumour angiogenesis and growth in both animal models and preclinical trials. However, the content of copper in pancreatic duct adenocarcinoma (PDAC) and...

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Detalles Bibliográficos
Autores principales: Yu, Ze, Zhou, Rongtao, Zhao, Yicheng, Pan, Yi, Liang, Hao, Zhang, Jin‐San, Tai, Sheng, Jin, Liang, Teng, Chun‐Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496122/
https://www.ncbi.nlm.nih.gov/pubmed/30706544
http://dx.doi.org/10.1111/cpr.12568

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