Pharmacokinetic-Pharmacodynamic Assessment of the Hepatic and Bone Marrow Toxicities of the New Trypanoside Fexinidazole

Fexinidazole is a novel oral treatment for human African trypanosomiasis caused by Trypanosoma brucei gambiense (g-HAT). Fexinidazole also has activity against T. cruzi, the causative agent of Chagas disease. During the course of a dose ranging assessment in patients with chronic indeterminate Chaga...

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Detalles Bibliográficos
Autores principales: Watson, James A., Strub-Wourgraft, Nathalie, Tarral, Antoine, Ribeiro, Isabela, Tarning, Joel, White, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496162/
https://www.ncbi.nlm.nih.gov/pubmed/30670439
http://dx.doi.org/10.1128/AAC.02515-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496162/
https://www.ncbi.nlm.nih.gov/pubmed/30670439
http://dx.doi.org/10.1128/AAC.02515-18

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